刘哲,女,1978年,2016年毕业于黑龙江八一农垦大学,农学博士学位。副教授/硕士研究生导师,黑龙江省细胞生物学学会成员。先后主持省部级教学及科研项目2项,横向科研项目1项,黑龙江八一农垦大学大学生创新创业训练计划项目1项。发表论文20余篇,其中SCI收录论文6篇。出版专著2部。主要从事微量元素、动物免疫和药理细胞毒理检测的研究,在学术上取得了一定成绩。主要承担细胞工程等本科生课程的教学任务。
◆ 教研成果
(1)项目及获奖
“应用为导向”的生物专业产业创新创业人才培养模式研究,黑龙江省教育厅,2021年,第1;
校级教育教学成果一等奖,基于科研社团模式下创新创业教育与实践教学深度融合的人才培养体系的构建与应用,2023年,第3
(2)论文及教材
1) Zhe Liu, Jingwei Wang, Zhiming Liang, Hongbo An, Liyang Li, Zhongjing Zang, Jing Li, Yang Xi, Tong Han, Shaobin Liu and Cheng-Hao Jin,Teaching Reform to the Biology Major During the COVID-19 Pandemic: A Study of the Method of Teaching Industrial Innovation and Entrepreneurial Talents. Frontiers in Psychology, 2020.5. doi: 10.3389/fpsyg.2022.843485.(SSCI; IF=4.232)
2) Hongbo An, Zhe Liu*, Shuang Zhang, Yanhong Wang, Jingwei Wang, Zhongjing Zang, Liyang Li. Construction of Training Program for Industrial Innovation and Entrepreneurship Talents ——Take the Bioengineering Major of Heilongjiang Bayi Agricultural University as an Example.Scholars Journal of Agriculture and Veterinary Sciences, 2022,11:3.
3) Zhongjing Zang, Jingwei Wang, Yanhong Wang, Hongbo An, Liyang Li, Tang Yanjun, Junying Zhang, Tianyang Bao, Zhe Liu*. Practice and Exploration of Integrating Industrial Innovation and Entrepreneurship with ApplicationOriented Talent Cultivation -- A Case Study of Bioengineering Major , Scholars Journal of Agriculture and Veterinary Sciences, 2022, 6: 30.
(3)指导学生“双创”情况
梁志明、郑添文. 第五届全国大学生生命科学竞赛(硒酵母减轻小鼠肠缺血-再灌注损伤的初步研究),国家二等奖(CULSC2022KE0030);第八届全国大学生生命科学竞赛委员会, 2022.8
◆ 科研成果:
(1)项目及获奖
多维硒钙铁锌锰咀嚼片的制备及安全性试验(2021081), 横向科研项目省级, 30.0万元, 2021.12-2022.7,主持
(2)论文及专著
1. Zhe Liu, Guangze Mou, Zhiming Liang, Rui Zhao, Chenghao Jin*, Rui Wu*. Selenomethionine Alleviates Intestinal Ischemia-Reperfusion Injury in Mice Through the Bax-Caspase Pathway. Biol Trace Elem Res. 2021, 18. doi: 10.1007/s12011-021-02925-6.
2. Zhe Liu, Feng Zhang, Lina Cui, Jihong Wang, Ping Lu, Rui Zhao, Hua Zhang, Jianfa Wang, Chunqiu Li, Rui Wu*. Quantitative proteomic analysis reveals that the Rap1/MAPK/ERK pathway is inhibited through selenomethionine strengthening antioxidant activity. BioMetals, 2020, 33, 45-64.
3. Liu Zhe, Zhang Feng, Lu Ping, Zhao Rui, Zhang Hua, Song Baifen, Li Liyang, Wu Zhijun, Wu Rui*. Selenium-Yeast Alleviated Inflammatory Damage Caused by Lead via Inhibiting Ras/ERK Pathway and Inflammatory Factors in Chicken Skeletal Muscles. Biol Trace Elem Res, 2019, 190 (2):493-500.
4. Liu Zhe, Yao Xiao, Du Juan, Song B, Zhang Feng*. Selenium Deficiency Augments the Levels of Inflammatory Factors and Heat Shock Proteins via the Redox Regulatory Pathway in the Skeletal Muscles of Mice.Biol Trace Elem Res, 2018 (2)182: 309-316.
5. Liu Zhe, Qu Y, Wang J, Wu Rui*. Selenium Deficiency Attenuates Chicken Duodenal MucosalImmunity via Activation of the NF-b Signaling Pathway. Biol Trace Elem Res, 2016, 172, (2): 465-473.
6. Wang Jianfa, Liu Zhe, He Xian, Lian Shuai, Liang Jian, Yu D. Sun Dongbo, Wu Rui*. Selenium deficiency induces duodenal villi cell apoptosis via an oxidative stress-induced mitochondrial apoptosis pathway and an inflammatory signaling-induced death receptor pathway, Metallomics, 2018, 17;10(10): 1390-1400.
刘哲,王建发,武瑞. 微量元素硒与动物免疫功能,东北林业大学出版社,2020年4月第一版, 2020.
刘哲,李丽阳,郑小亮. 西洋参皂苷、树舌多糖和香菇多糖的功能研究,东北林业大学出版社,2022年4月第一版,2022.